SPL Set ID: f3231f1c-665e-4efa-baa1-83bf296b2f8f
1 drug(s) with this SPL Set ID
Neomycin and polymyxin B sulfates and bacitracin zinc ophthalmic ointment, USP is a sterile antimicrobial ointment for topical ophthalmic use. Each gram contains Actives: neomycin sulfate equivalent to 3.5 mg neomycin base, polymyxin B sulfate equivalent to 10,000 polymyxin B units, and bacitracin zinc equivalent to 400 bacitracin units; Inactives: white petrolatum and mineral oil. Neomycin sulfate is the sulfate salt of neomycin B and C, which are produced by the growth of Streptomyces fradiae Waksman (Fam. Streptomycetaceae). It has a potency equivalent of not less than 600 micrograms of neomycin standard per mg, calculated on an anhydrous basis. The structural formulae are: Polymyxin B sulfate is the sulfate salt of polymyxin B 1 and B 2 which are produced by the growth of Bacillus polymyxa (Prazmowski) Migula (Fam. Bacillaceae). It has a potency of not less than 6,000 polymyxin B units per mg, calculated on an anhydrous basis. The structural formulae are: Bacitracin zinc is the zinc salt of bacitracin, a mixture of related cyclic polypeptides (mainly bacitracin A) produced by the growth of an organism of the licheniformis group of Bacillus subtilis var Tracy. It has a potency of not less than 40 bacitracin units per mg. The structural formula for bacitracin A is: A picture containing text, diagram, font, map Description automatically generated A picture containing text, font, white, receipt Description automatically generated A picture containing line, diagram, text, font Description automatically generated