SPL Set ID: e3aeefc2-f44d-4337-9c2e-3dba44a89e48

ZYCUBO (copper histidinate) for injection is a copper replacement product. The chemical name is copper, (L-histidinato-ϰ N ,ϰ N 3,ϰO)(L-histidinato-ϰ N ,ϰO)-, ( SP -5-14-C)-. The molecular formula is C 12 H 16 CuN 6 O 4 , and the molecular weight is 371.84 g/mol. Copper histidinate is soluble in water. The chemical structure is: ZYCUBO is a sterile, preservative-free, blue lyophilized powder or cake for subcutaneous injection after reconstitution with 1 mL sterile 0.9% Sodium Chloride Injection, USP. Each single-dose vial contains 2.9 mg of copper histidinate (equivalent to 0.5 mg elemental copper). The resultant solution has a concentration of 2.9 mg/mL and a pH of 7.4. Chemical Structure