SPL Set ID: d3fabf12-354e-4e5c-b5de-20fdb579b783
1 drug(s) with this SPL Set ID
HERNEXEOS tablets for oral administration contain zongertinib, a kinase inhibitor. The chemical name of zongertinib is 2-Propenamide, N -[1-[8-[[3-methyl-4-[(1-methyl-1 H -benzimidazol-5-yl)oxy]phenyl] amino]pyrimido[5,4- d ]pyrimidin-2-yl]-4-piperidinyl]-. Its molecular formula is C 29 H 29 N 9 O 2 and the molecular weight is 535.6. The structural formula is: Zongertinib is a yellow to dark yellow or orange solid. Zongertinib is slightly soluble at pH 1.2, and practically insoluble at pHs 3.6, 4.5, 5.4 and 6.8. Each film-coated tablet of HERNEXEOS contains 60 mg of zongertinib and the following inactive ingredients: colloidal silicon dioxide, croscarmellose sodium, hypromellose acetate succinate, mannitol, microcrystalline cellulose, and sodium stearyl fumarate. In addition, the film-coating contains the following inactive ingredients: ferric oxide (yellow), glycerol mono and dicaprylocaprate, polyvinyl alcohol, sodium lauryl sulfate, talc, and titanium dioxide. Chemical Structure