SPL Set ID: d3c528d2-429d-4f37-9ebf-eee8b9fd3050
1 drug(s) with this SPL Set ID
Tretinoin Gel Microsphere, 0.1%, 0.08% and 0.04% is a white to very pale yellow opaque gel for topical treatment of acne vulgaris. Chemically, tretinoin is all-trans-retinoic acid, also known as (all-E)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid. It is a member of the retinoid class of compounds and a metabolite of naturally occurring Vitamin A. Tretinoin has a molecular weight of 300.44, a molecular formula of C 20 H 28 O 2 and the following chemical structure: Each gram of Tretinoin Gel Microsphere, 0.1%, contains 1 mg of tretinoin. Each gram of Tretinoin Gel Microsphere, 0.08%, contains 0.8 mg of tretinoin. Each gram of Tretinoin Gel Microsphere, 0.04%, contains 0.4 mg of tretinoin. The formulation contains methyl methacrylate/glycol dimethacrylate crosspolymer (MICROSPONGE ® System), propylene glycol dicaprylate/dicaprate and butylated hydroxytoluene to enable inclusion of the active ingredient, tretinoin, in an aqueous gel. Other components consist of benzyl alcohol, butylated hydroxytoluene, carbomer 974P, cyclomethicone and dimethicone copolyol, disodium EDTA, glycerin, PPG-20 methyl glucose ether distearate, propylene glycol, purified water, sorbic acid, and trolamine. chemstructure.jpg