SPL Set ID: 472bd78e-be17-4b9d-90f4-9482c3aec9ff
1 drug(s) with this SPL Set ID
Trabectedin is an alkylating drug with the chemical name (1' R ,6 R ,6a R ,7 R ,13 S ,14 S ,16 R )-5-(acetyloxy)-3',4',6,6a,7,13,14,16-octahydro-6',8,14-trihydroxy-7',9-dimethoxy-4,10,23-trimethyl-spiro[6,16-(epithiopropanoxymethano)-7,13-imino-12 H -1,3-dioxolo[7,8]isoquino[3,2- b ][3]benzazocine-20,1'(2' H )-isoquinolin]-19-one. The molecular formula is C 39 H 43 N 3 O 11 S. The molecular weight is 761.84 daltons. The chemical structure is shown below: Trabectedin is hydrophobic and has a low solubility in water. YONDELIS ® (trabectedin) for injection is supplied as a sterile lyophilized white to off-white powder/cake in a single-dose vial. Each single-dose vial contains 1 mg of trabectedin, 27.2 mg potassium dihydrogen phosphate, 400 mg sucrose, and phosphoric acid and potassium hydroxide (for pH adjustment to 3.6 – 4.2). Chemical Structure