SPL Set ID: 2166bbdf-eb12-4564-b9e4-b63ca21312bc

Lenalidomide, a thalidomide analogue, is an immunomodulatory agent with antiangiogenic and antineoplastic properties. The chemical name is 3-(7-amino-3-oxo-1H-isoindol-2-yl) piperidine-2,6-dione and it has the following chemical structure: 3-(7-amino-3-oxo-1H-isoindol-2-yl) piperidine-2,6-dione The molecular formula for lenalidomide is C 13 H 13 N 3 O 3, and the gram molecular weight is 259.26. Lenalidomide is white to yellow crystalline powder. It is practically insoluble in isopropanol and ethanol. Very slightly soluble in water. Slightly soluble in acetonitrile and methanol. Lenalidomide has an asymmetric carbon atom and can exist as the optically active forms S(-) and R(+), and is produced as a racemic mixture with a net optical rotation of zero. Lenalidomide is available in 2.5 mg, 5 mg, 10 mg, 15 mg, 20 mg, and 25 mg capsules for oral administration. Each capsule contains lenalidomide as the active ingredient and the following inactive ingredients: croscarmellose sodium, magnesium stearate, mannitol, and microcrystalline cellulose. The 5 mg and 25 mg capsule shells contain gelatin, titanium dioxide, and black ink. The 2.5 mg and 10 mg capsule shells contain FD&C blue #2, gelatin, titanium dioxide, yellow iron oxide, and black ink. The 15 mg capsule shells contain FD&C blue #2, gelatin, titanium dioxide, and black ink. The 20 mg capsule shells contain FD&C blue #2, gelatin, titanium dioxide, yellow iron oxide, and black ink. The capsules are printed with black ink composed of ammonia solution, black iron oxide, potassium hydroxide, propylene glycol, and shellac. chemical structure