trandolapril - Medications

Trandolapril is the ethyl ester prodrug of a nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor, trandolaprilat. Trandolapril is chemically described as (2S,3aR,7aS)-1-[(S)-N-[(S)-1-Carboxy-3-phenylpropyl]alanyl] hexahydro-2-indolinecarboxylic acid, 1-ethyl ester. Its molecular formula is C 24 H 34 N 2 O 5 and its structural formula is M.W. = 430.54 Melting Point = 125°C Trandolapril USP is a white or almost white powder that is soluble (>100 mg/mL) in chloroform, dichloromethane, and methanol. Trandolapril tablets USP contain 1 mg, 2 mg, or 4 mg of trandolapril USP for oral administration. Each tablet also contains lactose monohydrate, corn starch, croscarmellose sodium, hypromellose, povidone, and sodium stearyl fumarate. In addition 1 mg and 4 mg tablet also contains ferric oxide red and 2 mg tablet contains ferric oxide yellow. Chemical Structure

Trandolapril is the ethyl ester prodrug of a nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor, trandolaprilat. Trandolapril is chemically described as (2S,3aR,7aS)-1-[(S)-N-[(S)-1-Carboxy-3-phenylpropyl]alanyl] hexahydro-2-indolinecarboxylic acid, 1-ethyl ester. Its molecular formula is C 24 H 34 N 2 O 5 and its structural formula is M.W. = 430.54 Melting Point = 125°C Trandolapril USP is a white or almost white powder that is soluble (>100 mg/mL) in chloroform, dichloromethane, and methanol. Trandolapril tablets USP contain 1 mg, 2 mg, or 4 mg of trandolapril USP for oral administration. Each tablet also contains lactose monohydrate, corn starch, croscarmellose sodium, hypromellose, povidone, and sodium stearyl fumarate. In addition 1 mg and 4 mg tablet also contains ferric oxide red and 2 mg tablet contains ferric oxide yellow. Chemical Structure

Trandolapril is the ethyl ester prodrug of a nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor, trandolaprilat. Trandolapril is chemically described as (2S,3aR,7aS)-1-[(S)-N-[(S)-1-Carboxy-3-phenylpropyl] alanyl] hexahydro-2-indolinecarboxylic acid, 1-ethyl ester. Its empirical formula is C 24 H 34 N 2 O 5 and its structural formula is Image M.W.=430.54 Melting Point=125°C Trandolapril is a white or almost white powder that is soluble (>100 mg/mL) in chloroform, dichloromethane, and methanol. Trandolapril tablets USP contain 1 mg, 2 mg, or 4 mg of trandolapril for oral administration. Each tablet also contains croscarmellose sodium, hypromellose, lactose monohydrate, povidone, starch (corn starch), sodium stearyl fumarate, red iron oxide or yellow iron oxide.

Trandolapril is the ethyl ester prodrug of a nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor, trandolaprilat. Trandolapril is chemically described as (2S,3aR,7aS)-1-[(S)-N-[(S)-1-Carboxy-3-phenylpropyl] alanyl] hexahydro-2-indolinecarboxylic acid, 1-ethyl ester. Its empirical formula is C 24 H 34 N 2 O 5 and its structural formula is Image M.W.=430.54 Melting Point=125°C Trandolapril is a white or almost white powder that is soluble (>100 mg/mL) in chloroform, dichloromethane, and methanol. Trandolapril tablets USP contain 1 mg, 2 mg, or 4 mg of trandolapril for oral administration. Each tablet also contains croscarmellose sodium, hypromellose, lactose monohydrate, povidone, starch (corn starch), sodium stearyl fumarate, red iron oxide or yellow iron oxide. image

Trandolapril is the ethyl ester prodrug of a nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor, trandolaprilat. Trandolapril is chemically described as (2S,3aR,7aS)-1-[(S)-N-[(S)-1-Carboxy-3-phenylpropyl]alanyl] hexahydro-2-indolinecarboxylic acid, 1-ethyl ester. Its molecular formula is C 24 H 34 N 2 O 5 and its structural formula is M.W. = 430.54 Melting Point = 125°C Trandolapril USP is a white or almost white powder that is soluble (>100 mg/mL) in chloroform, dichloromethane, and methanol. Trandolapril tablets USP contain 1 mg, 2 mg, or 4 mg of trandolapril USP for oral administration. Each tablet also contains lactose monohydrate, corn starch, croscarmellose sodium, hypromellose, povidone, and sodium stearyl fumarate. In addition 1 mg and 4 mg tablet also contains ferric oxide red and 2 mg tablet contains ferric oxide yellow.

Trandolapril is the ethyl ester prodrug of a nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor, trandolaprilat. Trandolapril is chemically described as (2S, 3aR, 7aS)-1-[(S)-N-[(S)-1-Carboxy-3-phenylpropyl]alanyl] hexahydro-2-indolinecarboxylic acid, 1- ethyl ester. Its empirical formula is C 24 H 34 N 2 O 5 and its structural formula is: M.W. = 430.54 Melting Point = 125°C Trandolapril is a white or almost white powder that is soluble (> 100 mg/mL) in chloroform, dichloromethane, and methanol. Trandolapril tablets contain 1 mg, 2 mg, or 4 mg of trandolapril USP for oral administration. Each tablet also contains corn starch, croscarmellose sodium, hypromellose, ferric oxide red, lactose monohydrate, povidone and sodium stearyl fumarate. Structural Formula - Trandolapril

Trandolapril and verapamil hydrochloride extended-release tablets combine a slow release formulation of a calcium channel blocker, verapamil hydrochloride, USP, and an immediate release formulation of an angiotensin converting enzyme inhibitor, trandolapril, USP. Verapamil Component Verapamil hydrochloride, USP is chemically described as benzeneacetonitrile, α [3-[[2-(3,4-dimethoxyphenyl) -ethyl] methylamino] propyl] -3,4-dimethoxy-α -(1-methylethyl)-, monohydrochloride, (±). Its molecular formula is C 27 H 38 N 2 O 4 • HCl and its structural formula is: Verapamil hydrochloride, USP is a white or practically white crystalline powder, with a molecular weight of 491.06 g/mol. It is soluble in water, freely soluble in chloroform, sparingly soluble in alcohol and practically insoluble in ether. It is practically odorless and has a bitter taste. verapamil-structure Trandolapril Component Trandolapril, USP is the ethyl ester prodrug of a nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor, trandolaprilat. It is chemically described as (2S,3aR,7aS)- 1- [(S)-2-[[(S)-1-(EthoxyCarbonyl)-3-phenylpropyl] amino]Propanoyl]octahydro-1H-indole-2-carboxylic acid. Its molecular formula is C 24 H 34 N 2 O 5 and its structural formula is: Trandolapril, USP is a white or almost white powder with a molecular weight of 430.54 g/mol. It is practically insoluble in water; freely soluble in methylene chloride; sparingly soluble in absolute alcohol. Trandolapril and verapamil hydrochloride extended-release tablets are formulated for oral administration, containing verapamil hydrochloride, USP as a controlled release formulation and trandolapril, USP as an immediate release formulation. The tablet strengths are trandolapril and verapamil hydrochloride extended-release tablets 1 mg/240 mg, trandolapril and verapamil hydrochloride extended-release tablets 2 mg/180 mg, trandolapril and verapamil hydrochloride extended-release tablets 2 mg/240 mg, and trandolapril and verapamil hydrochloride extended-release tablets 4 mg/240 mg. The tablets also contain the following ingredients: colloidal silicon dioxide, corn starch, croscarmellose sodium, ferric oxide red, hypromellose, lactose monohydrate, povidone, sodium alginate, sodium stearyl fumarate, magnesium stearate, and microcrystalline cellulose. The film coating contains: 1 mg/240 mg – hypromellose, titanium dioxide, and polyethylene glycol; 2 mg/180 mg – hypromellose, titanium dioxide, polyethylene glycol, iron oxide red, and FD&C blue #2; 2 mg/240 mg – hypromellose, titanium dioxide, polyethylene glycol, iron oxide yellow, iron oxide black, and iron oxide red; 4 mg/240 mg – hypromellose, titanium dioxide, polyethylene glycol, iron oxide yellow, iron oxide red, and iron oxide black. trandolapril-structure