sorafenib tosylate - Medications
Browse 3 medications containing sorafenib tosylate. Open a product record to review formulation details, related brands, manufacturers, and label-backed information.
Sorafenib, a kinase inhibitor, is the tosylate salt of sorafenib. Sorafenib tosylate, USP has the chemical name 4-(4-{3-[4-Chloro-3-(trifluoromethyl)phenyl]ureido}phenoxy)-N2-methylpyridine-2-carboxamide 4-methylbenzenesulfonate. The molecular formula of sorafenib tosylate, USP is C 21 H 16 ClF 3 N 4 O 3 .C 7 H 8 O 3 S and the molecular weight of sorafenib tosylate, USP is 637.03 grams/mole. Its structural formula is: Sorafenib tosylate, USP is a white or slightly yellowish or brownish powder. Sorafenib tosylate, USP is soluble in polyethylene glycol 400, slightly soluble in ethanol, and practically insoluble in aqueous media (i.e. water) and in heptane. Sorafenib tablets, USP for oral use are supplied as film-coated tablets containing 200 mg of sorafenib equivalent to 274 mg sorafenib tosylate, USP and the following inactive ingredients: croscarmellose sodium, hypromellose, iron oxide yellow, magnesium stearate, microcrystalline cellulose, polyethylene glycol, sodium lauryl sulphate, talc and titanium dioxide. FDA approved dissolution test specifications differ from USP.
Sorafenib, a kinase inhibitor, is the tosylate salt of sorafenib. Sorafenib tosylate, USP has the chemical name 4-(4-{3-[4-Chloro-3-(trifluoromethyl)phenyl]ureido}phenoxy)N2-methylpyridine-2-carboxamide 4-methylbenzene sulfonate. The molecular formula of sorafenib tosylate, USP is C 21 H 16 ClF 3 N 4 O 3 x C 7 H 8 O 3 S and the molecular weight of sorafenib tosylate, USP is 637.03 g/mole. Its structural formula is: Sorafenib tosylate, USP is a white to yellowish or brownish solid. Sorafenib tosylate, USP is practically insoluble in aqueous media, slightly soluble in ethanol and soluble in PEG 400. Sorafenib tablets, USP for oral use is supplied as film-coated tablets containing 200 mg sorafenib equivalent to 274 mg sorafenib tosylate, USP and the following inactive ingredients: croscarmellose sodium, hypromellose 2910, iron oxide red, magnesium stearate, microcrystalline cellulose, polyethylene glycol 400, sodium lauryl sulfate, and titanium dioxide. 1
Sorafenib, a kinase inhibitor, is the tosylate salt of sorafenib. Sorafenib tosylate, USP has the chemical name 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]- N -methylpyridine-2-carboxamide, tosylate. The molecular formula of sorafenib tosylate, USP is C 21 H 16 ClF 3 N 4 O 3• C 7 H 8 O 3 S and the molecular weight of sorafenib tosylate, USP is 637.03 g/mole. Its structural formula is: Sorafenib tosylate, USP is a cream to yellow crystalline powder. Sorafenib tosylate, USP is practically insoluble in aqueous media, slightly soluble in ethanol and soluble in PEG 400. Sorafenib tablets, USP for oral use are supplied as film-coated tablets containing 200 mg sorafenib equivalent to 274 mg sorafenib tosylate, USP and the following inactive ingredients: carboxymethylcellulose calcium, croscarmellose sodium, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, red iron oxide, sodium lauryl sulfate and titanium dioxide. Sorafenib Tosylate Structural Formula
About sorafenib tosylate
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