nintedanib esylate - Medications

Browse 1 medications containing nintedanib esylate. Open a product record to review formulation details, related brands, manufacturers, and label-backed information.

Ofev NINTEDANIB
(NINTEDANIB) 150 mg Capsule
BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. FDA Rx Only

OFEV capsules contain nintedanib, a kinase inhibitor [see Mechanism of Action (12.1) ]. Nintedanib is presented as the ethanesulfonate salt (esylate), with the chemical name 1 H -Indole-6-carboxylic acid, 2,3-dihydro-3-[[[4-[methyl[(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-,methyl ester, (3 Z )-, ethanesulfonate (1:1). Its structural formula is: Nintedanib esylate is a bright yellow powder with an empirical formula of C 31 H 33 N 5 O 4 ∙C 2 H 6 O 3 S and a molecular weight of 649.76 g/mol. OFEV capsules for oral administration are available in 2 dose strengths containing 100 mg or 150 mg of nintedanib (equivalent to 120.40 mg or 180.60 mg nintedanib ethanesulfonate, respectively). The inactive ingredients of OFEV are the following: Fill Material: hard fat, lecithin, triglycerides. Capsule Shell: ferric oxide red, ferric oxide yellow, gelatin, glycerol, titanium dioxide. Chemical Structure

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