istradefylline - Medications

Browse 1 medications containing istradefylline. Open a product record to review formulation details, related brands, manufacturers, and label-backed information.

NOURIANZ ISTRADEFYLLINE
KYOWA KIRIN, INC. FDA Rx Only

NOURIANZ contains istradefylline, an adenosine receptor antagonist, which has a xanthine derivative structure. The chemical name is ( E )-8-(3,4-dimethoxystyryl)-1,3-diethyl-7-methyl-3,7-dihydro-1 H -purine-2,6-dione. Its molecular formula is C 20 H 24 N 4 O 4 . The molecular weight is 384.43. Istradefylline has the following structural formula: Istradefylline is a light yellow-green crystalline powder. Istradefylline has a dissociation constant (p K a ) of 0.78. The aqueous solubility of istradefylline is ~0.5 µg/mL across the physiological pH range and 0.6 µg/mL in water. NOURIANZ tablets are intended for oral administration only. Each tablet contains 20 mg or 40 mg of istradefylline and the following inactive ingredients: crospovidone, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and polyvinyl alcohol. The film coating contains hypromellose, lactose monohydrate, polyethylene glycol 3350, titanium dioxide, triacetin, and the following dyes: iron oxide red and iron oxide yellow. Carnauba wax is used for polishing. Chemical Structure

About istradefylline

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