dextroamphetamine - Medications

XELSTRYM (dextroamphetamine) transdermal system, contains dextroamphetamine, a CNS stimulant. Dextroamphetamine is the dextro isomer of the compound d , l -amphetamine. The chemical name for dextroamphetamine is (2S)-1-phenylpropan-2-amine. It is a clear to slightly amber colored liquid. Molecular weight of dextroamphetamine is 135.21 g/mol and the molecular formula is C 9 H 13 N. The chemical structure is: XELSTRYM is provided in four strengths: 4.5 mg/9 hours, 9 mg/9 hours, 13.5 mg/9 hours, and 18 mg/9 hours. The composition per unit area of all dosage strengths is identical. Inactive ingredients include: acrylic adhesives, green ink, polyester/polyurethane backing, and polyester release liner. Table 4: XELSTRYM (dextroamphetamine) transdermal system Dosage Strength (dextroamphetamine) Dextroamphetamine Content per Transdermal System Transdermal System Size 4.5 mg / 9 hours 5 mg 4.76 cm 2 9 mg / 9 hours 10 mg 9.52 cm 2 13.5 mg / 9 hours 15 mg 14.29 cm 2 18 mg / 9 hours 20 mg 19.05 cm 2 Transdermal System Components XELSTRYM consists of three layers ( Figure 1 ). The layers are (1) oversized protective silicone-coated polyester release liner that is removed and discarded prior to application (2) acrylic adhesive matrix containing dextroamphetamine, and (3) polyester and polyurethane laminate film (backing). Figure 1: XELSTRYM Transdermal System (Exploded View) chemical structure Figure1