caffeine - Medications

Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate Capsules are supplied in capsule form for oral administration. Each capsule contains: Butalbital, USP 50 mg Acetaminophen, USP 325 mg Caffeine, USP 40 mg Codeine phosphate, USP 30 mg Butalbital (5-allyl-5-isobutylbarbituric acid), is a short-to intermediate-acting barbiturate. It has the following structural formula: C 11 H 16 N 2 O 3 MW 224.26 Acetaminophen (4'hydroxyacetanilide), is a non-opiate, non-salicylate analgesic and antipyretic. It has the following structural formula: C 8 H 9 NO 2 MW 151.16 Caffeine (1,3,7-trimethylxanthine), a methylxanthine, is a central nervous system stimulant. It has the following structural formula: C 8 H 10 N 4 O 2 MW 194.19 Codeine phosphate (7,8-Didehydro-4,5α-epoxy-3-methoxy-17-methylmorphinan-6α-ol phosphate (1:1)(salt) hemihydrate) is an opioid agonist. It has the following structural formula: C 18 H 24 NO 7 P anhydrous MW 397.37 Inactive Ingredients: Microcrystalline Cellulose, Sodium Lauryl Sulfate, Stearic Acid, Talc. The gelatin capsules are printed with edible inks containing Titanium Dioxide, Gelatin, FD&C Blue No. 1, FD&C Red No. 40, and FD&C Yellow No. 5 [see Warnings and Precautions (5.21) ]. Chemical Structure Chemical Structure Chemical Structure Chemical Structure

Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate Capsules are supplied in capsule form for oral administration. Each capsule contains: Butalbital, USP ...................................................................................... 50 mg Acetaminophen, USP ............................................................................. 325 mg Caffeine, USP ........................................................................................ 40 mg Codeine Phosphate, USP ......................................................................... 30 mg Butalbital (5-allyl-5-isobutylbarbituric acid), is a short-to intermediate-acting barbiturate. It has the following structural formula: Acetaminophen (4'-hydroxyacetanilide), is a non-opiate, non-salicylate analgesic and antipyretic. It has the following structural formula: Caffeine (1,3,7-trimethylxanthine), a methylxanthine, is a central nervous system stimulant. It has the following structural formula: Codeine phosphate (7,8-Didehydro-4,5_-epoxy-3-methoxy-17-methylmorphinan-6_-ol phosphate (1:1) (salt) hemihydrate), is an opioid agonist. It has the following structural formula: Inactive Ingredients: Microcrystalline Cellulose, Sodium Lauryl Sulfate, Stearic Acid, Talc. The gelatin capsules are printed with edible inks containing Titanium Dioxide, Gelatin, FD&C Blue No. 1, FD&C Red No. 3, FD&C Red No. 40 and FD&C Yellow No. 5. [see Warnings and Precautions (5.21)] . A chemical structure with black text Description automatically generated A chemical structure with black text Description automatically generated A chemical structure with black text Description automatically generated A chemical formula of a molecule Description automatically generated

Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate Capsules are supplied in capsule form for oral administration. Each capsule contains: Butalbital, USP…………..........50 mg Acetaminophen, USP………...325 mg Caffeine, USP……………........40 mg Codeine phosphate, USP….......30 mg Butalbital (5-allyl-5-isobutylbarbituric acid), is a short-to intermediate-acting barbiturate. It has the following structural formula: Acetaminophen (4'hydroxyacetanilide), is a non-opiate, non-salicylate analgesic and antipyretic. It has the following structural formula: Caffeine (1,3,7trimethylxanthine), a methylxanthine, is a central nervous system stimulant. It has the following structural formula: Codeine phosphate (7,8-Didehydro-4,5α-epoxy-3-methoxy-17-methylmorphinan-6α-ol phosphate (1:1)(salt) hemihydrate) is an opioid agonist. It has the following structural formula: Inactive Ingredients: colloidal silicon dioxide, magnesium stearate, pregelatinized starch. Gelatin capsules contain D&C Red No. 33, FD&C Blue No. 1, gelatin, and titanium dioxide. The capsules are printed with edible inks containing D&C Red No. 7 Calcium Lake, FD&C Blue No. 1 Aluminum Lake, and titanium dioxide. chem-structure-but.jpg chem-structure-acet.jpg chem-structure-caff.jpg chem-structure-cod.jpg

Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate Capsules are supplied in capsule form for oral administration. Each capsule contains: Butalbital, USP…………..........50 mg Acetaminophen, USP………...300 mg Caffeine, USP……………........40 mg Codeine phosphate, USP….......30 mg Butalbital (5-allyl-5-isobutylbarbituric acid), is a short-to intermediate-acting barbiturate. It has the following structural formula: Acetaminophen (4'hydroxyacetanilide), is a non-opiate, non-salicylate analgesic and antipyretic. It has the following structural formula: Caffeine (1,3,7-trimethylxanthine), a methylxanthine, is a central nervous system stimulant. It has the following structural formula: Codeine phosphate (7,8-Didehydro-4,5α-epoxy-3-methoxy-17-methylmorphinan-6α-ol phosphate (1:1)(salt) hemihydrate) is an opioid agonist. It has the following structural formula: Inactive Ingredients: FD&C blue #1, FD&C red #40, FD&C yellow #6, gelatin, microcrystalline cellulose, stearic acid, sodium lauryl sulfate, talc, and titanium dioxide. Butalbital Structural Formula Acetaminophen Caffeine Codeine phosphate

Butalbital, aspirin, and caffeine capsules, USP are supplied in capsule form for oral administration. Each capsule contains the following active ingredients: butalbital, USP 50 mg aspirin, USP 325 mg caffeine, USP 40 mg Butalbital (5-allyl-5-isobutylbarbituric acid) is a short- to intermediate-acting barbiturate. It has the following Molecular Formula: C 11 H 16 N 2 O 3 Molecular Weight: 224.26 Structural Formula: Aspirin (benzoic acid, 2-(acetyloxy)-) is an analgesic, antipyretic, and anti-inflammatory. It has the following Molecular Formula: C 9 H 8 O 4 Molecular Weight: 180.16 Structural Formula: Caffeine (1, 3, 7-trimethylxanthine) is a central nervous system stimulant. It has the following Molecular Formula: C 8 H 10 N 4 O 2 Molecular Weight: 194.19 Structural Formula: Inactive Ingredients: pregelatinized starch, microcrystalline cellulose, sodium starch glycolate, trimyristin, talc, colloidal silicon dioxide, D&C Yellow No. 10, FD&C Green No. 3, and gelatin. The capsule imprinting ink contains: shellac glaze in ethanol, iron oxide black, n-butyl alcohol, propylene glycol, ethanol, methanol, FD&C Blue No. 2 Aluminum Lake, FD&C Red No. 40 Aluminum Lake, FD&C Blue No. 1 Aluminum Lake, and D&C Yellow No.10 Aluminum Lake. butalbital-chemical-structure aspirin-chemical-structure caffeine-chemical-structure

Butalbital, aspirin, and caffeine capsules are supplied in capsule form for oral administration. Each capsule contains the following active ingredients: butalbital, USP.......................... 50 mg aspirin, USP.............................. 325 mg caffeine, USP............................ 40 mg Butalbital (5-allyl-5-isobutylbarbituric acid) is a short- to intermediate-acting barbiturate. It has the following structural formula: Aspirin (benzoic acid, 2-(acetyloxy)-) is an analgesic, antipyretic, and anti-inflammatory. It has the following structural formula: Caffeine (1, 3, 7-trimethylxanthine) is a central nervous system stimulant. It has the following structural formula: Inactive Ingredients: pregelatinized starch, microcrystalline cellulose, sodium starch glyco­late, trimyristin, talc, colloidal silicon dioxide, D&C Yellow No. 10, FD&C Green No. 3, and gelatin. The capsule imprinting ink contains: shellac glaze in ethanol, iron oxide black, n-butyl alcohol, propylene glycol, ethanol, methanol, FD&C Blue No. 2 Aluminum Lake, FD&C Red No. 40 Aluminum Lake, FD&C Blue No. 1 Aluminum Lake, and D&C Yellow No.10 Aluminum Lake. image description image description image description

Butalbital, Aspirin, and Caffeine Capsules, USP is supplied in capsule form for oral administration. Each capsule contains the following active ingredients: butalbital, USP . . . . . . . . . . . . 50 mg aspirin, USP . . . . . . . . . . . . . . 500 mg caffeine, USP . . . . . . . . . . . . . 40 mg Butalbital (5-allyl-5-isobutylbarbituric acid) is a short- to intermediate-acting barbiturate. It has the following structural formula: C 11 H 16 N 2 O 3 molecular weight 224.26 Aspirin (benzoic acid, 2-(acetyloxy)-) is an analgesic, antipyretic, and anti-inflammatory. It has the following structural formula: C 9 H 8 O 4 molecular weight 180.16 Caffeine (1,3,7-trimethylxanthine) is a central nervous system stimulant. It has the following structural formula: C 8 H 10 N 4 O 2 molecular weight 194.19 Inactive Ingredients: Microcrystalline cellulose, stearic acid, sodium lauryl sulfate, and talc. Gelatin capsules contain FD&C Blue No. 1, FD&C Green No. 3, FD&C Yellow No. 5, red iron oxide, yellow iron oxide, titanium dioxide and gelatin. The capsules are printed with edible ink. Butalbital (5-allyl-5-isobutylbarbituric acid) is a short- to intermediate-acting barbiturate. It has the following structural formula Aspirin (benzoic acid, 2-(acetyloxy)-) is an analgesic, antipyretic, and anti-inflammatory. It has the following structural formula Caffeine (1,3,7-trimethylxanthine) is a central nervous system stimulant. It has the following structural formula

Butalbital, aspirin, and caffeine capsules are supplied in capsule form for oral administration. Each capsule contains the following active ingredients: butalbital, USP.......................... 50 mg aspirin, USP.............................. 325 mg caffeine, USP............................ 40 mg Butalbital (5-allyl-5-isobutylbarbituric acid) is a short- to intermediate-acting barbiturate. It has the following structural formula: Aspirin (benzoic acid, 2-(acetyloxy)-) is an analgesic, antipyretic, and anti-inflammatory. It has the following structural formula: Caffeine (1, 3, 7-trimethylxanthine) is a central nervous system stimulant. It has the following structural formula: Inactive Ingredients: pregelatinized starch, microcrystalline cellulose, sodium starch glyco­late, trimyristin, talc, colloidal silicon dioxide, D&C Yellow No. 10, FD&C Green No. 3, and gelatin. The capsule imprinting ink contains: shellac glaze in ethanol, iron oxide black, n-butyl alcohol, propylene glycol, ethanol, methanol, FD&C Blue No. 2 Aluminum Lake, FD&C Red No. 40 Aluminum Lake, FD&C Blue No. 1 Aluminum Lake, and D&C Yellow No.10 Aluminum Lake. butalbital-molec-structure aspirin-molec-structure caffeine-molec-structure

Butalbital, Aspirin, and Caffeine Capsules, USP is supplied in capsule form for oral administration. Each capsule contains the following active ingredients: butalbital, USP 50 mg aspirin, USP 325 mg caffeine, USP 40 mg Butalbital (5-allyl-5-isobutylbarbituric acid) is a short- to intermediate-acting barbiturate. It has the following structural formula: C 11 H 16 N 2 O 3 molecular weight 224.26 Aspirin (benzoic acid, 2-(acetyloxy)-) is an analgesic, antipyretic, and anti-inflammatory. It has the following structural formula: C 9 H 8 O 4 molecular weight 180.16 Caffeine (1,3,7-trimethylxanthine) is a central nervous system stimulant. It has the following structural formula: C 8 H 10 N 4 O 2 molecular weight 194.19 Inactive Ingredients: lactose monohydrate, pregelatinized maize starch, sodium starch glycolate and talc. Gelatin capsule contains yellow iron oxide, FD&C Blue # 2, titanium dioxide and gelatin. The imprinting ink contains the following: black iron oxide, D&C Yellow # 10 Aluminum Lake, FD&C Blue #1/ Brilliant Blue FCF Aluminum Lake, FD&C Blue #2/ Indigo Carmine Aluminum Lake, FD&C Red # 40/ Allura Red AC Aluminum Lake, propylene glycol and shellac glaze. Chemical Structure Chemical Structure Chemical Structure

ASCOMP with Codeine (Butalbital, Aspirin, Caffeine, and Codeine Phosphate Capsules, USP) is supplied in capsule form for oral administration. Each capsule contains the following active ingredients: Butalbital, USP ................... 50mg Aspirin, USP ..................... 325mg Caffeine, USP ..................... 40mg Codeine phosphate, USP ..... 30mg Butalbital (5-allyl-5-isobutylbarbituric acid) is a short-to intermediate-acting barbiturate. It has the following structural formula: C 11 H 16 N 2 O 3 molecular weight 224.26 Aspirin (benzoic acid, 2-(acetyloxy)-) is a nonsteroidal anti-inflammatory drug. It has the following structural formula: C 9 H 8 O 4 molecular weight 180.16 Caffeine (1,3,7-trimethylxanthine), a methylxanthine, is a central nervous system stimulant. It has the following structural formula: C 8 H 10 N 4 O 2 molecular weight 194.19 Codeine phosphate (7,8-Didehydro-4,5α-epoxy-3-methoxy-17-methylmorphinan-6α-ol phosphate (1:1) (salt) hemihydrate) is an opioid agonist. It has the following structural formula: C 18 H 24 NO 7 P anhydrous molecular weight 397.37 Inactive Ingredients: Corn Starch, D&C Red No. 28, D&C Yellow No. 10, FD&C Blue No. 1, FD&C Red No. 40, Gelatin, Microcrystalline Cellulose, Sodium Lauryl Sulfate, Stearic Acid, Talc, and Titanium Dioxide. The capsules are printed with edible black ink.

BUTALBITAL, ASPIRIN, CAFFEINE and CODEINE PHOSPHATE USP is supplied in capsule form for oral administration. Each capsule contains the following active ingredients: Butalbital, USP……………..50 mg Aspirin, USP………………..325 mg Caffeine, USP………………40 mg Codeine phosphate, USP…...30 mg Butalbital (5-allyl-5-isobutyl-barbituric acid) is a short- to intermediate-acting barbiturate. It has the following structural formula: Its molecular weight is 224.26 and its molecular formula is C 11 H 16 N 2 O 3 . Aspirin (benzoic acid, 2-(acetyloxy)-) is a nonsteroidal anti-inflammatory drug. It has the following structural formula: Its molecular weight is 180.16 and its molecular formula is C 9 H 8 O 4 . Caffeine (1,3,7-trimethylxanthine), a methylxanthine, is a central nervous system stimulant. It has the following structural formula: Its molecular weight is 194.19 and its molecular formula is C 8 H 10 N 4 O 2 . Codeine phosphate (7,8-Didehydro-4,5α-epoxy-3-methoxy-17-methylmorphinan-6α-ol phosphate (1:1) (salt) hemihydrate) is an opioid agonist. It has the following structural formula: Its molecular weight is 397.37 and its molecular formula is C 18 H 24 NO 7 P. Inactive Ingredients : D&C Yellow #10, D&C Yellow #10 Aluminum Lake, D&C Red #33, D&C Red #28, FD&C Blue #1, FD&C Blue #1 Aluminum Lake, gelatin, microcrystalline cellulose, pregelatinized starch, talc, titanium dioxide, stearic acid, colloidal silicon dioxide. Butalbital Structural Formula Aspirin Structural Formula Caffeine Structural Formula Codeine Phosphate Structural Formula

Use helps restore mental alertness or wakefulness when experiencing fatigue or drowsiness

Uses helps restore mental alertness or wakefulness when experiencing fatigue or drowsiness

Uses helps restore mental alertness or wakefulness when experiencing fatigue or drowsiness

Uses helps restore mental alertness or wakefulness when experiencing fatigue or drowsiness

Use Helps restore mental alertness or wakefulness when experiencing fatigue or drowsiness

INDICATIONS For the temporary relief of hyperactivity, irritability, weak memory and concentration, anxiousness, occasional headache, or fatigue due to sensitivity to phenolic compounds found in foods or other products.*

Caffeine and Sodium Benzoate Injection, USP is a clear, sterile, nonpyrogenic, solution of Caffeine Alkaloid. Each mL contains: Caffeine (anhydrous) 125 mg; Sodium Benzoate (added to increase the solubility of Caffeine) 125 mg; Water for Injection, USP q.s. pH (range 6.5 to 8.5) adjusted with Hydrochloric Acid and/or Sodium Hydroxide. For intramuscular or slow intravenous administration only.

INDICATIONS For the temporary relief of headache, anxiousness, irritability, fatigue, and itching of the nose or throat due to sensitivity to caffeine.*

Summary not available yet.

Uses: temporarily relieves minor aches and pains associated with: headache, toothache, menstrual cramps, minor arthritis pain, muscular aches, colds, temporarily reduces fever.

Uses temporarily relieves minor aches and pain due to: headache muscular aches

USES: • For the temporary relief of symptoms including: • mucous congestion • nausea • drowsiness • lethargy • confusion • vaginal discharge • sensitivity to foods These statements are based upon homeopathic principles. They have not been reviewed by the Food and Drug Administration.

Use • treats migraine

Uses for the temporary relief of these symptoms associated with menstrual periods: cramps bloating water-weight gain headache backache breast tenderness fatigue muscle aches

Uses • temporarily relieves minor aches and pains due to: • headache • a cold • arthritis • muscular aches • toothache • premenstrual & menstrual cramps

Use • treats migraine

Use • treats migraine

Uses For the relief of temporary: water retention bloating swelling full feeling fatigue associated with the premenstrual and menstrual periods.

Uses For the relief of: temporary water retention bloating swelling full feeling fatigue associated with the pre-menstrual and menstrual periods

Uses For temporary relief of temporary water retention bloat swelling full feeling fatigue minor aches and pains associated with the premenstrual and menstrual periods.

Uses For relief of symptoms associated with the premenstrual and menstrual periods including: temporary water retention bloat swelling full feeling fatigue

Uses For the temporary relief of these symptoms associated with menstrual periods cramps bloating water- weight gain headache backache Muscle aches fatigue

Uses Temporarily relieves minor aches and pains due to: headache a cold arthritis muscular aches toothache premenstrual and menstrual cramps and bloating

Uses temporarily relieves minor aches and pains due to: headache toothache menstrual cramps muscular aches minor arthritis pain colds temporarily reduces fever

Uses For the temporary relief of minor aches and pains due to: toothache headache and to reduce fever

Uses temporarily relieves minor aches and pains due to: headache a cold arthritis muscular aches sinusitis toothache premenstrual and menstrual cramps

Uses temporarily relieves minor aches and pain due to: headache muscular aches

Uses temporarily relieves minor aches and pain due to: headache muscular aches

Uses Helps restore mental alertness or wakefulness when experiencing fatigue or drowsiness

Use • treats migraine

Each tablet for oral administration contains 1 mg ergotamine tartrate, USP, and 100 mg caffeine, USP. ERGOTAMINE TARTRATE: (C 33 H 35 N 5 O 5 ) 2 • C 4 H 6 O 6 M.W. 1313.41 Ergotaman-3’,6’,18-trione, 12’-hydroxy-2’-methyl-5’-(phenyl-methyl)-, (5’α), [R-(R*, R*)]-2,3-dihydroxy-butanedioate (2:1) (salt) CAFFEINE: C 8 H 10 N 4 O 2 (anhydrous) M.W. 194.19 1 H -Purine-2,6-dione, 3,7-dihydro-1,3,7-trimethyl- Inactive ingredients include colloidal silicon dioxide, crospovidone, magnesium stearate, and microcrystalline cellulose. Film coating includes the following ingredients: macrogol/PEG 3350, polyvinyl alcohol, purified water, talc, titanium dioxide, FD&C blue #2 aluminum lake, FD&C red #40 aluminum lake, and FD&C yellow #5 tartrazine aluminum lake. structure1 structure2

Uses temporarily relieves minor aches and pains due to: headache muscular aches minor arthritis pain backache common cold menstrual cramps toothache temporarily reduces fever

Uses • temporarily relieves minor aches and pains due to: • headache • a cold • arthritis • muscular aches • toothache • premenstrual & menstrual cramps

Uses temporarily relieves minor aches and pains due to: headache a cold arthritis muscular aches toothache premenstrual and menstrual cramps

Uses • temporarily relieves minor aches and pains due to: • headache • a cold • arthritis • muscular aches • toothache • premenstrual and menstrual cramps

Uses temporarily relieves minor aches and pains due to: headache a cold arthritis muscular aches toothache premenstrual and menstrual cramps

Uses • temporarily relieves minor aches and pains due to: • headache • a cold • arthritis • muscular aches • toothache • premenstrual and menstrual cramps

Uses temporarily relieves minor aches and pains due to: headache a cold arthritis muscular aches toothache premenstrual & menstrual cramps

Uses • temporarily relieves minor aches and pains due to: o headache o a cold o arthritis o muscular aches o toothache o premenstrual and menstrual cramps