SPL Set ID: fc401b06-4e3b-413e-a854-3e031c433862
1 drug(s) with this SPL Set ID
Nelarabine Injection is a prodrug of the cytotoxic deoxyguanosine analogue, 9-β- D -arabinofuranosylguanine (ara-G). The chemical name for nelarabine is 2-amino-9-β- D -arabinofuranosyl-6-methoxy-9H-purine. It has the molecular formula C 11 H 15 N 5 O 5 and a molecular weight of 297.27. Nelarabine has the following structural formula: Nelarabine Injection is supplied as a clear, colorless, sterile solution in glass single-dose vials. Each vial contains either 250 mg or 375 mg of nelarabine (5 mg nelarabine per mL) and the inactive ingredient sodium chloride (4.5 mg per mL) in 50 mL or 75 mL, respectively, Water for Injection, USP. Nelarabine Injection is intended for intravenous infusion. Nelarabine is slightly soluble to soluble in water and melts with decomposition between 209ºC and 217ºC. Hydrochloric acid and sodium hydroxide may have been used to adjust the pH. The solution pH ranges from 5.0 to 7.0. structure