SPL Set ID: f98314ea-a4e4-4f78-987b-3e9b45a08bb4
1 drug(s) with this SPL Set ID
Methylprednisolone Acetate Injectable Suspension, USP is an anti-inflammatory glucocorticoid for intramuscular, intra-articular, soft tissue, or intralesional injection. It is available in two strengths: 40 mg per mL, 80 mg per mL. Each mL of these preparations contains: Methylprednisolone acetate……………………………………40 mg……………………..80 mg Polyethylene glycol 3350……………………………………29.1 mg……………………28.2 mg Polysorbate 80.………………………………………………1.94 mg……………………1.88 mg Monobasic sodium phosphate…………………………………6.8 mg……………………6.59 mg Dibasic sodium phosphate, USP……………………………..1.42 mg…………………….1.37 mg Benzyl alcohol added as a preservative………………………9.16 mg……………………8.88 mg Sodium Chloride was added to adjust tonicity. When necessary, pH was adjusted with sodium hydroxide and/or hydrochloric acid. The pH of the finished product remains within the USP specified range (e.g., 3.5 to 7.0). The chemical name for methylprednisolone acetate is pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-11,17-dihydroxy-6-methyl-,(6α,11ß)- and the molecular weight is 416.51. The structural formula is represented below: Methylprednisolone Acetate Injectable Suspension, USP, sterile aqueous suspension, contains methylprednisolone acetate which is the 6-methyl derivative of prednisolone. Methylprednisolone acetate is a white or practically white, odorless, crystalline powder which melts at about 215° with some decomposition. It is soluble in dioxane, sparingly soluble in acetone, alcohol, chloroform, and methanol, and slightly soluble in ether. It is practically insoluble in water. Structural Formula