SPL Set ID: f94a5c9e-74bc-d09e-cd65-394b2a5de2ad
1 drug(s) with this SPL Set ID
Zoledronic acid injection contains zoledronic acid, a bisphosphonic acid which is an inhibitor of osteoclastic bone resorption. Zoledronic acid is designated chemically as (1-Hydroxy-2-imidazol-1-yl-phosphonoethyl) phosphonic acid monohydrate and its structural formula is: Zoledronic acid monohydrate, USP is white to almost white crystalline solid. Its molecular formula is C 5 H 10 N 2 O 7 P 2 . H 2 O and a molar mass of 290.1 g/Mol. Zoledronic acid monohydrate, USP is sparingly soluble in 0.1N sodium hydroxide solution. The pH of the zoledronic acid injection solution for infusion is approximately 6 to 7. Zoledronic acid injection is available as a sterile solution in bottles for intravenous infusion. One bottle with 100 mL solution contains 5.330 mg of zoledronic acid monohydrate, USP equivalent to 5 mg zoledronic acid on an anhydrous basis. Inactive Ingredients: 4950 mg of mannitol, USP; and 30 mg of sodium citrate, USP.