SPL Set ID: eac3fd1c-ca4b-4aa3-9dc2-e7dbeb4c122a

1 drug(s) with this SPL Set ID

Open DailyMed details

carboprost tromethamine CARBOPROST TROMETHAMINE
AMNEAL PHARMACEUTICALS LLC FDA Rx Only

Carboprost tromethamine injection USP, an oxytocic, contains the tromethamine salt of the (15S)-15 methyl analogue of naturally occurring prostaglandin F2α in a sterile solution suitable for intramuscular injection. Carboprost tromethamine USP, is the established name for the active ingredient in carboprost tromethamine injection, USP. Four other chemical names are: 1. (15S)-15-methyl prostaglandin F2α tromethamine salt 2. (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-(3S)-3-hydroxy-3-methyl-1-octenyl]cyclopentyl]-5-heptenoic acid compound with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1) 3. Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-15-methyl-, (5Z,9α,11α,13E,15S)-, compound with 2-amino-2-(hydroxy-methyl)-1,3-propanediol (1:1) The structural formula is represented below: The molecular formula is C 21 H 36 O 5 .C 4 H 11 NO 3 . The molecular weight of carboprost tromethamine, USP is 489.64. It is a white to off-white crystalline powder. It generally melts between 95° and 105°C, depending on the rate of heating. Carboprost tromethamine, USP dissolves readily in water at room temperature at a concentration greater than 75 mg/mL. Each mL of carboprost tromethamine injection, USP contains carboprost tromethamine, USP equivalent to 250 mcg of carboprost, 83 mcg tromethamine, 9 mg sodium chloride, and 9.45 mg benzyl alcohol added as preservative. When necessary, pH is adjusted with sodium hydroxide and/or hydrochloric acid. The solution is sterile. structure

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