SPL Set ID: e66665e8-22eb-f5cd-e053-2a95a90a72e4
1 drug(s) with this SPL Set ID
Diltiazem Hydrochloride is a calcium ion influx inhibitor (slow channel blocker or calcium antagonist). Chemically, diltiazem hydrochloride is 1,5-Benzothiazepin-4(5 H )one, 3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-, monohydrochloride, (+)-cis-. Its molecular formula is C 22 H 26 N 2 O 4 S•HCl and its molecular weight is 450.98. Its structural formula is as follows: Diltiazem hydrochloride is a white to off-white crystalline powder with a bitter taste. It is soluble in water, methanol, and chloroform. Diltiazem Hydrochloride Extended-Release Capsules, USP contain multiple units of diltiazem HCl extended-release 60 mg, resulting in 120 mg, 180 mg, or 240 mg dosage strengths allowing for the controlled release of diltiazem HCl over a 24-hour period. Inactive Ingredients: Diltiazem Hydrochloride Extended-Release Capsules, USP also contain colloidal silicon dioxide, ethylcellulose, hypromellose, magnesium stearate, medium chain triglycerides and oleic acid. The 120 mg, 180 mg and 240 mg capsule shells contain gelatin and titanium dioxide, ferric oxide yellow (120 mg and 180 mg), and ferric oxide red (180 mg and 240 mg). The imprinting ink contains ferrosoferric oxide, potassium hydroxide and shellac. For oral administration. Diltiazem Hydrochloride Extended-Release Capsules, USP meet USP Dissolution Test 28. Diltiazem hydrochloride Chemical Structure