SPL Set ID: e1d80a82-de52-4a34-9df3-609e50667ffb

Denosumab-dssb is a human IgG2 monoclonal antibody with affinity and specificity for human RANKL (receptor activator of nuclear factor kappa-B ligand). Denosumab-dssb has an approximate molecular weight of 147 kDa and is produced in genetically engineered mammalian (Chinese hamster ovary) cells. Ospomyv (denosumab-dssb) injection is a sterile, preservative-free, clear, colorless to slightly yellow solution for subcutaneous use. Each single-dose prefilled syringe contains1 mL solution of 60 mg denosumab-dssb, 0.28 mg histidine, 3.81 mg histidine hydrochloride monohydrate, 0.1 mg polysorbate 20, 44 mg sorbitol, and Water for Injections. The pH is 5.2.