SPL Set ID: e16012ae-5972-470b-8a22-b0626a029e95
1 drug(s) with this SPL Set ID
Tolterodine tartrate extended-release capsules contain tolterodine tartrate USP. The active moiety, tolterodine, is a muscarinic receptor antagonist. The chemical name of tolterodine tartrate USP is (R)-2-[3-[Bis (1-methylethyl) amino]-1-phenylpropyl]-4-Methyl phenol [R-(R*,R*)]-2, 3-dihydroxybutanedioate (1:1) (salt). The empirical formula of tolterodine tartrate USP is C 22 H 31 NO.C 4 H 6 O 6 . Its structure is: Tolterodine tartrate USP is a white to off white crystalline powder with a molecular weight of 475.57. The pKa value is 9.24 and the solubility in water is 12 mg/mL. It is soluble in dimethylformamide and in methanol. The partition coefficient (Log P) value is 2.6. Tolterodine tartrate extended-release capsules, 2 mg and 4 mg for oral administration contains 2 mg and 4 mg of tolterodine tartrate USP respectively. Inactive ingredients are aqueous ethylcellulose dispersion, dehydrated alcohol, dibasic calcium phosphate anhydrous, ethyl acrylate and methyl methacrylate copolymer dispersion, ethyl cellulose, FD & C Blue 2, gelatin, hypromellose, methylene chloride, microcrystalline cellulose, talc and titanium dioxide. Additionally 2 mg capsules contain iron oxide yellow. Both the 2 mg and 4 mg strengths capsule shells are imprinted with a pharmaceutical grade printing ink that contains butyl alcohol, dehydrated alcohol, isopropyl alcohol, potassium hydroxide, propylene glycol, shellac, strong ammonia solution and titanium dioxide. Tolterodinetartratestructure