SPL Set ID: e05e3314-5520-4bbd-b7f0-623afd9ba569
1 drug(s) with this SPL Set ID
Each Triamterene and hydrochlorothiazide capsule, USP for oral use, with opaque red cap and opaque white body, contains hydrochlorothiazide 25 mg and triamterene 37.5 mg, and is imprinted with "T 49" on the body with black ink. Hydrochlorothiazide is a diuretic/antihypertensive agent and triamterene is an antikaliuretic agent. Hydrochlorothiazide, USP is slightly soluble in water. It is soluble in dilute ammonia, dilute aqueous sodium hydroxide, and dimethylformamide. It is sparingly soluble in methanol. Hydrochlorothiazide, USP is 6-chloro-3,4-dihydro-2H-1, 2, 4-benzothiadiazine-7-sulfonamide 1,1-dioxide, and its structural formula is: At 50°C, triamterene, USP is practically insoluble in water (less than 0.1%). It is soluble in formic acid, sparingly soluble in methoxyethanol, and very slightly soluble in alcohol. Triamterene, USP is 2, 4, 7-triamino-6-phenylpteridine and its structural formula is: Inactive ingredients consist of microcrystalline cellulose, lactose monohydrate, sodium starch glycolate, cetylpyridinium chloride, povidone, polysorbate 80, glycine, magnesium stearate. The capsule shells have the following inactive ingredients: gelatin, D&C Red No. 33, FD&C Yellow No. 6 and titanium dioxide. The black ink has the following inactive ingredients: shellac, propylene glycol, black iron oxide E172 and potassium hydroxide. FDA approved dissolution test specifications differ from USP 178 159