SPL Set ID: dbf738c4-3fac-4422-a9d8-51d9c83a8789
1 drug(s) with this SPL Set ID
Infliximab-abda, a tumor necrosis factor (TNF) blocker, is a chimeric IgG1κ monoclonal antibody (composed of human constant and murine variable regions). It has a molecular weight of approximately 149.1 kilodaltons. Infliximab-abda is produced by a recombinant murine myeloma cell line, SP2/0. RENFLEXIS ® (infliximab-abda) for injection is supplied as a sterile, preservative-free, white, lyophilized powder for intravenous infusion after reconstitution and dilution. Following reconstitution with 10 mL of Sterile Water for Injection, USP, the final concentration is 10 mg/mL and the resulting pH is approximately 6. Each single-dose vial contains 100 mg infliximab-abda, dibasic sodium phosphate heptahydrate (1.2 mg), monobasic sodium phosphate monohydrate (6.3 mg), polysorbate 80 (0.5 mg), and sucrose (500 mg).