SPL Set ID: d83c6ae4-a41c-4b14-94b3-2d93c9aa28d1

Colchicine is an alkaloid obtained from the plant colchicum autumnale . The chemical name for colchicine is ( S)-N- (5,6,7,9- tetrahydro-1,2,3,10-tetramethoxy-9 oxobenzol[a]heptalen-7-yl) acetamide. The structural formula is represented below: Colchicine consists of pale yellow to pale greenish-yellow amorphous scales or powder or crystalline powder; it darkens on exposure to light. Colchicine is soluble in water, freely soluble in alcohol and in chloroform; slightly soluble in ether. Colchicine capsules are supplied for oral administration. Each capsule contains 0.6 mg colchicine, USP and the following inactive ingredients: colloidal silicon dioxide, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and sodium starch glycolate. The capsule shell contains FD&C Blue No. 1, FD&C Red No. 40, gelatin and titanium dioxide. The capsules are imprinted with black ink containing black iron oxide, potassium hydroxide and shellac.