SPL Set ID: d0a7247c-5d83-4bc1-840f-c58314d14195
1 drug(s) with this SPL Set ID
Fluvastatin sodium is a water-soluble cholesterol lowering agent which acts through the inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. Fluvastatin sodium is Sodium (±)-(3 R *,5 S *,6 E )-7-[3-( p -fluorophenyl)-1-isopropylindol-2-yl]-3,5-dihydroxy-6-heptenoate. The molecular formula of fluvastatin sodium is C 24 H 25 FNNaO 4 , its molecular weight is 433.45 and its structural formula is: This molecular entity is the first entirely synthetic HMG-CoA reductase inhibitor, and is in part structurally distinct from the fungal derivatives of this therapeutic class. Fluvastatin sodium, USP is an off-white to yellow, hygroscopic powder soluble in water, ethanol and methanol. Fluvastatin is supplied as capsules containing fluvastatin sodium, equivalent to 20 mg or 40 mg of fluvastatin, for oral administration. Active ingredient: fluvastatin sodium Inactive ingredients in capsules: corn starch, crospovidone, gelatin, magnesium stearate, red iron oxide, sodium lauryl sulfate, talc, titanium dioxide and yellow iron oxide. In addition, the black imprinting ink for the 20 mg and 40 mg capsules contains ammonium hydroxide, black iron oxide, propylene glycol and shellac glaze. Fluvastatin Structural Formula