SPL Set ID: ce5f4f14-5e60-4cc1-bcb3-1fa9b8aa9cd5
1 drug(s) with this SPL Set ID
Tretinoin gel USP, 0.05% is a translucent to opaque, pale yellow topical gel containing 0.05% tretinoin, by weight for topical administration. Chemically, tretinoin is all- trans -retinoic acid, also known as (all- E )-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid. It is a member of the retinoid class of compounds, and a metabolite of Vitamin A. Tretinoin has a molecular weight of 300.44, a molecular formula of C 20 H 28 O 2 and the following structure: Each gram of tretinoin gel, 0.05% contains 0.5 mg of tretinoin, USP. Other components of this formulation are benzyl alcohol, butyl paraben, butylated hydroxytoluene, carbomer 980, ethyl paraben, fish collagen hydrolyzates, glycerin, iso-butyl paraben, methylparaben, octoxynol 9, phenoxyethanol, propylparaben, purified water, sodium hyaluronate, and trolamine. The contribution to efficacy of individual components of the vehicle has not been evaluated. Tretinoin Structural Formula