SPL Set ID: ccf2c4b1-e9a3-c7b7-ac42-79e1988fc211
1 drug(s) with this SPL Set ID
Febuxostat is a xanthine oxidase inhibitor. The active ingredient in febuxostat is 2-[3-cyano-4-(2-methylpropoxy) phenyl]-4-methylthiazole-5-carboxylic acid, with a molecular weight of 316.37. The molecular formula is C 16 H 16 N 2 O 3 S. The chemical structure is: Febuxostat is a white to off white color powder that is freely soluble in dimethylformamide; soluble in dimethylsulfoxide; sparingly soluble in ethanol; slightly soluble in methanol and acetonitrile; and practically insoluble in water. The melting range is 205°C to 208°C. Febuxostat tablets for oral use contain the active ingredient, febuxostat, and are available in two dosage strengths, 40 mg and 80 mg. Inactive ingredients include ammonium hydroxide, colloidal silicon dioxide, croscarmellose sodium, hydroxypropyl cellulose, hypromellose, iron oxide black, iron oxide yellow, magnesium stearate, mannitol, microcrystalline cellulose, polyethylene glycol, propylene glycol, shellac and titanium dioxide.