SPL Set ID: c7026b15-1228-4acb-beed-4474fcdbb972

Phenylephrine is an alpha-1 adrenergic receptor agonist. Phenylephrine Hydrochloride Injection, USP, 10 mg/mL, is a clear, colorless, sterile, nonpyrogenic solution for intravenous use. It must be diluted before administration as an intravenous bolus or continuous intravenous infusion. The chemical name of Phenylephrine hydrochloride is (-)- m -hydroxy-α- [(methylamino)methyl]benzyl alcohol hydrochloride and is chemically designated as C 9 H 14 C1NO 2 with a molecular weight of 203.67 g/mol. Its structural formula is depicted below: Phenylephrine hydrochloride is soluble in water and ethanol, and insoluble in chloroform and ethyl ether. Phenylephrine Hydrochloride Injection, USP 10 mg/mL, is sensitive to light. Each mL contains: Phenylephrine hydrochloride 10 mg, sodium chloride 3.5 mg, sodium citrate dihydrate 4 mg, and citric acid 1 mg in water for injection. The pH is adjusted with sodium hydroxide and/or hydrochloric acid if necessary. The pH range is 3.5-5.5. Structural Formula