SPL Set ID: c2d2e3a1-f346-4245-b445-6dd44e371180
1 drug(s) with this SPL Set ID
Tacrolimus Ointment contains tacrolimus, USP a macrolide immunosuppressant produced by Streptomyces tsukubaensis . It is for topical dermatologic use only. Chemically, tacrolimus, USP is designated as (-)-(3 S ,4 R ,5 S ,8 R ,9 E ,12 S ,14 S ,15 R ,16 S ,18 R ,19 R ,26a S )-8-Allyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25, 26,26a-hexadecahydro-5,19-dihydroxy-3-[( E )-2-[(1 R ,3 R ,4 R )-4-hydroxy-3-methoxycyclohexyl]-1-methylvinyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3 H -pyrido[2,1-c][1,4] oxaazacyclotricosine-1,7,20,21(4 H ,23 H )-tetrone,monohydrate. It has the following structural formula: Tacrolimus, USP has a molecular formula of C 44 H 69 NO 12 •H 2 O and a formula weight of 822.03. Each gram of tacrolimus ointment contains either 0.03% or 0.1% w/w of tacrolimus, USP in a base of mineral oil, paraffin, propylene carbonate, white petrolatum and white wax. structure.jpg