SPL Set ID: bf4d29c8-4731-42bc-887a-d8302add9ca9
1 drug(s) with this SPL Set ID
Febuxostat is a xanthine oxidase inhibitor. The active ingredient in febuxostat is 2-[3-cyano-4-(2-methylpropoxy) phenyl]-4-methylthiazole-5-carboxylic acid hemihydrate, with a molecular weight of 325.39. The molecular formula is C 16 H 16 N 2 O 3 S 1 / 2 H 2 O. The chemical structure is: Febuxostat is a non-hygroscopic, white to yellowish crystalline powder that is soluble in dimethyl formamide, slightly soluble in methanol and insoluble in water. The melting range is 207 o C to 210°C. Febuxostat tablets for oral use contain the active ingredient, febuxostat, and are available in two dosage strengths, 40 mg and 80 mg. Inactive ingredients include colloidal silicon dioxide, croscarmellose sodium, hydroxypropyl cellulose, lactose monohydrate, microcrystalline cellulose and magnesium stearate. Febuxostat tablets are coated with polyvinyl alcohol, macrogol, titanium dioxide, talc, D&C yellow #10 aluminum lake, FD&C blue #1/brilliant blue FCF aluminum lake, FD&C blue #2/indigo carmine AL 3%-5% (40 mg), additionally iron oxide yellow (80 mg). febu-str