SPL Set ID: bbf275df-2fe0-443c-99ca-2298721441dc

Clomipramine Hydrochloride Capsules USP is an antiobsessional drug that belongs to the class (dibenzazepine) of pharmacologic agents known as tricyclic antidepressants. Clomipramine hydrochloride capsules USP is available as capsules of 25, 50, and 75 mg for oral administration. Clomipramine hydrochloride USP is 3-chloro-5-[3-(dimethylamino) propyl]-10,11-dihydro- 5H - dibenz[ b,f ] azepine monohydrochloride, and its structural formula is: C 19 H 23 ClN 2 ·HCl MW = 351.31 Clomipramine hydrochloride USP is a white or slightly yellow, crystalline powder. It is very soluble in water, freely soluble in dichloromethane and soluble in 96% ethanol. Inactive Ingredients . Inactive ingredients in clomipramine hydrochloride capsule , USP : colloidal silicon dioxide, FD & C Blue No. 1, FD & C Red No. 40, gelatin, lactose monohydrate, magnesium stearate, pregelatinized starch (maize), titanium dioxide.Clomipramine Hydrochloride Capsules, USP 25 mg also contain: D & C Red No. 28, FD & C Yellow No. 6, D & C Yellow No. 10. Clomipramine Hydrochloride Capsules, USP 50 mg also contain: FD & C Red No. 3. Clomipramine Hydrochloride Capsules, USP 75 mg also contain: D & C Red No. 28, FD & C Yellow No. 6. In addition, the black imprinting ink for the 25 mg, 50 mg and 75 mg capsules contains: black iron oxide, potassium hydroxide, propylene glycol, and shellac. FDA approved dissolution test specifications differ from USP.