SPL Set ID: b92628dd-fa09-4c3a-b6a3-66426025807c
1 drug(s) with this SPL Set ID
Bortezomib, a proteasome inhibitor, is an antineoplastic agent available for intravenous or subcutaneous injection. The chemical name for bortezomib {(1 R )-3-Methyl-1-[(2 S )-3-phenyl-2-(pyrazin-2-carboxamido)propanamido]butyl}boronic acid. The structural formula is as follows: The molecular formula of bortezomib is C 19 H 25 BN 4 O 4 ; it has a molecular weight of 384.24. Bortezomib is freely soluble in methanol, ethanol and dimethyl sulfoxide, practically insoluble in toluene, pH range of 4 to 6.5. BORUZU is available as a single-dose vial containing 3.5 mg of bortezomib as a sterile solution. Each 1 mL of solution contains 2.5 mg bortezomib, 25 mg mannitol, sodium chloride for isotonicity and water for injection. 1