SPL Set ID: b8b50bd9-bc1b-4da5-96c5-8eb917c8937f
1 drug(s) with this SPL Set ID
Cimetidine is a histamine H 2 -receptor antagonist. Chemically it is N”- cyano- N-methyl-N’ -[2-[[(5- methyl-1 H -imidazol-4-yl) methyl]thio]-ethyl], guanidine. The molecular formula for cimetidine hydrochloride is C 10 H 16 N 6 S•HCI and the molecular weight is 288.80. The structural formula of cimetidine hydrochloride is: Cimetidine contains an imidazole ring, and is chemically related to histamine. Cimetidine has a bitter taste and characteristic odor. chemical structure Solubility Characteristics Cimetidine hydrochloride is freely soluble in water, soluble in alcohol, very slightly soluble in chloroform and practically insoluble in ether. Each 5 mL (1 teaspoonful), for oral administration, contains cimetidine hydrochloride equivalent to cimetidine, 300 mg; alcohol, 2.8%. In addition, the oral solution contains the following inactive ingredients: FD&C Yellow No. 6, hydrochloric acid, methylparaben, poloxamer 188, propylene glycol, propylparaben, purified water, saccharin sodium, sodium chloride, dibasic sodium phosphate anhydrous, and sorbitol. The pH range is 5.1 to 5.7.