SPL Set ID: b650e8b6-6df7-4301-837d-3d3b650b7456
1 drug(s) with this SPL Set ID
Ziprasidone hydrochloride capsules are available for oral administration. Ziprasidone is a psychotropic agent that is chemically unrelated to phenothiazine or butyrophenone antipsychotic agents. It has a molecular weight of 412.94 (free base), with the following chemical name: 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2 H -indol-2-one. The molecular formula of C 21 H 21 ClN 4 OS (free base of ziprasidone) represents the following structural formula: Ziprasidone hydrochloride capsules contain a monohydrochloride, anhydrous salt of ziprasidone. Chemically, ziprasidone hydrochloride anhydrous is 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2 H -indol-2-one, monohydrochloride, anhydrous. The molecular formula is C 21 H 21 ClN 4 OS · HCl and its molecular weight is 449.4. Ziprasidone hydrochloride anhydrous is a light pink to dark pink colored powder. Ziprasidone hydrochloride capsules are supplied for oral administration in 20 mg (yellow/blue), 40 mg (blue/blue), 60 mg (yellow/yellow), and 80 mg (yellow/blue) capsules. Ziprasidone hydrochloride capsule, intended for oral administration, contains ziprasidone hydrochloride anhydrous equivalent to 20 mg, 40 mg, 60 mg or 80 mg of ziprasidone. In addition, each capsule contains the following inactive ingredients: calcium silicate, citric acid, lactose anhydrous, magnesium stearate and pregelatinized starch. The capsule shell for the 20 mg and 80 mg strengths consists of carboxymethylcellulose, FD&C blue # 2, gelatin, iron oxide yellow, sodium lauryl sulfate and titanium dioxide. The capsule is printed with edible black pharmaceutical ink. The capsule shell for the 40 mg strength consists of FD&C blue # 2, gelatin, sodium lauryl sulfate and titanium dioxide. The capsule is printed with edible white pharmaceutical ink. The capsule shell for the 60 mg strength consists of carboxymethylcellulose, gelatin, iron oxide yellow, sodium lauryl sulfate and titanium dioxide. The capsule is printed with edible black pharmaceutical ink. The black ink is comprised of iron oxide black, potassium hydroxide, propylene glycol, shellac and ammonia solution. The white ink is comprised of povidone, propylene glycol, sodium hydroxide, shellac and titanium dioxide. structural formula