SPL Set ID: b5463553-b775-47a3-8d10-31e01ca1ec72
1 drug(s) with this SPL Set ID
NALOXONE HYDROCHLORIDE injection, USP, for intramuscular or subcutaneous use, is an opioid antagonist in a pre-filled, single-dose auto-injector containing 10 mg of naloxone HCl in 0.4 mL solution. NALOXONE HYDROCHLORIDE injection is not made with natural rubber latex. Chemically, naloxone HCl is the hydrochloride salt of 17-Allyl-4,5α-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride with the following structure: C 19 H 21 NO 4 HC1 M.W.363.84 Naloxone HCl occurs as a white to slightly off-white powder, and is soluble in water, in dilute acids, and in strong alkali; slightly soluble in alcohol; practically insoluble in ether and in chloroform. Each 0.4 mL of NALOXONE HYDROCHLORIDE injection contains 10 mg of naloxone HCl (equivalent to 9.0 mg naloxone base), 3.34 mg of sodium chloride, hydrochloric acid to adjust pH, and water for injection. The pH range is 3.0 to 4.5. chemical structure