SPL Set ID: b4ef805f-9fc3-47f7-b1f7-328c54970e5d
1 drug(s) with this SPL Set ID
Chlordiazepoxide hydrochloride and clidinium bromide capsules, USP are a fixed-combination of chlordiazepoxide hydrochloride, a benzodiazepine, and clidinium bromide, an anticholinergic. Each chlordiazepoxide hydrochloride and clidinium bromide capsules, USP contain the active ingredients 5 mg chlordiazepoxide hydrochloride, USP and 2.5 mg clidinium bromide, USP. Each capsule also contains the inactive ingredients D&C Yellow No. 10, FD & C Blue 1, FD&C Green No. 3, gelatin, hydrogenated castor oil, lactose monohydrate, maize starch, titanium dioxide, and purified water. Each capsule is imprinted with black pharmaceutical ink which contains: butyl alcohol, dehydrated alcohol, ferrosoferric oxide, isopropyl alcohol, potassium hydroxide, propylene glycol, purified water, shellac and strong ammonia solution. Chlordiazepoxide hydrochloride, USP is 7-chloro-2-(methylamino)-5-phenyl-3 H -1,4-benzodiazepine 4-oxide monohydrochloride. A white to slightly yellow crystalline powder, it is sparingly soluble in alcohol (ethanol 96%) and insoluble in hexane. It is unstable in solution and the powder must be protected from light. The molecular formula is C 16 H 15 Cl 2 N 3 O and molecular weight is 336.22 g/mol. The structural formula of chlordiazepoxide hydrochloride, USP is as follows: Clidinium bromide, USP is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have an antispasmodic and antisecretory effects on the gastrointestinal tract. Clidinium bromide, USP is white to off white crystalline powder. It is soluble in methanol and practically insoluble in ether. The chemical name is (±)-3-hydroxy-1-methylquinuclidinium bromide benzilate, molecular formula is C 22 H 26 BrNO 3 and molecular weight is 432.36 g/mol. Structurally, clidinium bromide, USP is: Meets USP Dissolution Test 2. 1 1