SPL Set ID: b1f0590e-f5bb-44ac-99a0-4aa4596c7e54

Denosumab-nxxp is a human IgG2 monoclonal antibody that binds to human RANKL. Denosumab-nxxp has an approximate molecular weight of 147 kDa and is produced in genetically engineered mammalian (Chinese hamster ovary) cells. Bilprevda (denosumab-nxxp) injection is a sterile, preservative-free, clear to slightly opalescent, colorless to slightly yellow solution for subcutaneous use. Each single-dose vial contains 120 mg denosumab-nxxp, glacial acetic acid (1.84 mg), polysorbate 20 (0.17 mg), sorbitol (78.2 mg), Water for Injection (USP), and sodium hydroxide to a pH of 5.2.