SPL Set ID: b165df31-52f0-d67f-71e7-f3b4f18d2f15
1 drug(s) with this SPL Set ID
Zoledronic acid injection contains zoledronic acid, a bisphosphonic acid which is an inhibitor of osteoclastic bone resorption. Zoledronic acid is designated chemically as (1-Hydroxy-2-imidazol-1-yl-phosphonoethyl) phosphonic acid monohydrate and its structural formula is Zoledronic acid is white to almost white crystalline solid. Its molecular formula is C 5 H 10 N 2 O 7 P 2 • H 2 O and its molar mass is 290.1g/Mol. Zoledronic acid is sparingly soluble in 0.1N sodium hydroxide solution. The pH of a 0.7% aqueous solution of zoledronic acid is between 1.5 and 2.5. Zoledronic acid injection is available in 100 mL bottle as a sterile liquid ready-to-use solution for intravenous infusion. Each 100 mL ready-to-use bottle contains 4.264 mg of zoledronic acid monohydrate, corresponding to 4 mg zoledronic acid on a dried basis, 5100 mg of mannitol, USP, water for injection, and 24 mg of sodium citrate, USP. Inactive Ingredients: mannitol USP, as bulking agent, sodium citrate USP, as buffering agent and water for injection as vehicle.