SPL Set ID: a6a8a8ba-3966-4f37-a58b-44d3b05bdc4e
1 drug(s) with this SPL Set ID
Nisoldipine is an extended-release tablet dosage form of the dihydropyridine calcium channel blocker nisoldipine. Nisoldipine is (±)-Isobutyl methyl 1,4-dihydro-2,6-dimethyl-4-( o -nitrophenyl)-3,5-pyridinedicarboxylate, C 20 H 24 N 2 O 6 , and has the structural formula: Nisoldipine is a yellow crystalline powder, practically insoluble in water but soluble in acetone, ethanol and methanol. It has a molecular weight of 388.4. Nisoldipine extended-release tablets contain 20 mg, 30 mg or 40 mg of nisoldipine for once-a-day oral administration. Inactive ingredients include: colloidal silicon dioxide, hydroxypropyl cellulose, hypromellose, lactose monohydrate, magnesium stearate, polydextrose, polyethylene glycol and titanium dioxide. The 20 mg tablets also contain FD&C Blue No. 2 Aluminum Lake, FD&C Yellow No. 6 Aluminum Lake and triacetin. The 30 mg tablets also contain red iron oxide, triacetin and yellow iron oxide. The 40 mg tablets also contain D&C Yellow No. 10 Aluminum Lake, FD&C Blue No. 2 Aluminum Lake and FD&C Yellow No. 6 Aluminum Lake. Nisoldipine Structural Formula