SPL Set ID: a48a3a33-6b0e-4cf4-8786-8f662d6ee77b

Denosumab-qbde is a human IgG2 monoclonal antibody that binds to human RANKL. Denosumab-qbde has an approximate molecular weight of 147 kDa and is produced in genetically engineered mammalian (Chinese hamster ovary) cells. Xtrenbo (denosumab-qbde) injection is a sterile, preservative-free, clear to slightly opalescent, colorless to pale yellow solution for subcutaneous use. Each single-dose vial contains 120 mg denosumab-qbde, glacial acetic acid (1.8375 mg), polysorbate 20 (0.17 mg), sorbitol (78.2 mg), Water for Injection (USP). Sodium hydroxide may be added to adjust pH to approximately 5.2.