SPL Set ID: a3976cf9-9edb-4ca2-9375-9bcd2e32f5b4

Bevacizumab-tnjn is a vascular endothelial growth factor inhibitor. Bevacizumab-tnjn is a recombinant humanized monoclonal IgG1 antibody that contains human framework regions and murine complementarity-determining regions. Bevacizumab-tnjn has an approximate molecular weight of 149 kDa. Bevacizumab-tnjn is produced in a mammalian cell (Chinese Hamster Ovary) expression system. Avzivi (bevacizumab-tnjn) injection is a sterile, preservative-free, clear to slightly opalescent, colorless to pale brown solution in a single-dose vial for intravenous use. Avzivi contains bevacizumab-tnjn at a concentration of 25 mg/mL in either a 100 mg/4 mL or 400 mg/16 mL single-dose vial. Each mL of solution contains 25 mg bevacizumab-tnjn, dibasic sodium phosphate (1.2 mg), monobasic sodium phosphate (5 mg), polysorbate 20 (0.4 mg), trehalose (54.3 mg) , and Water for Injection, USP. The pH is 6.1.