SPL Set ID: a363f0cd-9c8e-4622-9271-171706846b96
1 drug(s) with this SPL Set ID
Methylprednisolone acetate injectable suspension, USP is a sterile anti-inflammatory glucocorticoid for intramuscular, intra-articular, soft tissue, or intralesional injection. It is available in 40 mg/mL, 80 mg/mL strength: Each mL of these preparations contains: Methylprednisolone acetate.................................. 40 mg 80 mg Polyethylene glycol 3350................................... 29.1 mg 28.2 mg Polysorbate 80.................................................... 1.94 mg 1.88 mg Monobasic sodium phosphate monohydrate........ 6.8 mg 6.59 mg Dibasic sodium phosphate anhydrous USP........ 1.42 mg 1.37 mg Benzyl alcohol added as a preservative............... 9.16 mg 8.88 mg Sodium Chloride was added to adjust tonicity. When necessary, pH was adjusted with sodium hydroxide and/or hydrochloric acid. The pH of the finished product remains within the USP specified range (e.g., 3.5 to 7.0). The chemical name for methylprednisolone acetate is pregna-1,4-diene-3,20- dione, 21-(acetyloxy)-11,17-dihydroxy-6-methyl-,(6α,11β) and 11β,17,21-Trihydroxy-6α-methylpregna-1,4-diene-3,20-dione 21-acetate the molecular weight is 416.51. The structural formula is represented below: Methylprednisolone acetate sterile aqueous suspension contains methylprednisolone acetate which is the 6-methyl derivative of prednisolone. Methylprednisolone acetate is a white or practically white, odorless, crystalline powder which melts at about 215° with some decomposition. It is soluble in dioxane, sparingly soluble in acetone, alcohol, chloroform, and methanol, and slightly soluble in ether. It is practically insoluble in water. MPA Structure