SPL Set ID: a27d0815-ae6b-4a21-a8f5-564c01e83814

Mepivacaine hydrochloride is 2-Piperidinecarboxamide, N-(2, 6-dimethylphenyl)-1-methyl-, monohydrochloride and has the following structural formula: C 15 H 22 N 2 O • HCl It is a white, crystalline, odorless powder, soluble in water, but very resistant to both acid and alkaline hydrolysis. Mepivacaine hydrochloride is a local anesthetic available as sterile isotonic solutions (clear, colorless) in concentrations of 1%, 1.5% and 2% for injection via local infiltration, peripheral nerve block, and caudal and lumbar epidural blocks. Mepivacaine hydrochloride is related chemically and pharmacologically to the amide-type local anesthetics. It contains an amide linkage between the aromatic nucleus and the amino group. Composition of Available Solutions* 1% Single Dose 30 mL Vial mg/mL 1% Multiple Dose 50 mL Vial mg/mL 1.5% Single Dose 30 mL Vial mg/mL 2% Single Dose 20 mL Vial mg/mL 2% Multiple Dose 50 mL Vial mg/mL Mepivacaine hydrochloride 10 10 15 20 20 Sodium chloride 6.6 7 5.6 4.6 5 Potassium chloride 0.3 0.3 0.3 Calcium chloride 0.33 0.33 0.33 Methylparaben 1 1 *In Water For Injection The pH of the solution is adjusted between 4.5 and 6.8 with sodium hydroxide or hydrochloric acid. structure