SPL Set ID: a1e768fd-c28f-4b49-822d-ccc315b4099c
1 drug(s) with this SPL Set ID
Bupropion hydrochloride extended-release tablets (XL), an antidepressant of the aminoketone class, is chemically unrelated to tricyclic, tetracyclic, selective serotonin reuptake inhibitor, or other known antidepressant agents. Its structure closely resembles that of diethylpropion; it is related to phenylethylamines. It is designated as (±)-1-(3-chorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone hydrochloride. The molecular weight is 276.2. The molecular formula is C 13 H 18 ClNO•HCl. Bupropion hydrochloride powder is white, crystalline, and highly soluble in water. It has a bitter taste and produces the sensation of local anesthesia on the oral mucosa. The structural formula is: Bupropion hydrochloride extended-release tablets (XL) are supplied for oral administration as 150 mg, white to off-white extended-release tablets. Each tablet contains the labeled amount of bupropion hydrochloride, USP and the inactive ingredients: colloidal silicon dioxide, ethylcellulose, hydroxypropyl cellulose, methacrylic acid and ethyl acrylate copolymer, microcrystalline cellulose, stearic acid, talc, titanium dioxide, and triethyl citrate. The tablets are printed with edible black ink which consists of the following: hypromellose 2910, iron oxide black, and propylene glycol. Meets USP dissolution method 28. Structural formula