SPL Set ID: a0cbcdb5-f657-49f7-8f86-cc5959d69db0
1 drug(s) with this SPL Set ID
Methylprednisolone acetate injectable suspension, USP is an anti-inflammatory glucocorticoid for intramuscular, intra-articular, soft tissue, or intralesional injection. It is available in two strengths: 40 mg/mL, 80 mg/mL. Each mL of these preparations contains: Methylprednisolone acetate USP………………………………...…... 40 mg 80 mg Polyethylene glycol 3350 ……………………………………...……. 29.1 mg 28.2 mg Polysorbate 80 ………………………………………………............. 1.94 mg 1.88 mg Monobasic sodium phosphate ………………………………............. 6.8 mg 6.59 mg Dibasic sodium phosphate USP…………………………………...…. 1.42 mg 1.37 mg Benzyl alcohol added as a preservative……………………............... 9.16 mg 8.88 mg Sodium Chloride was added to adjust tonicity. When necessary, pH was adjusted with sodium hydroxide and/or hydrochloric acid. The pH of the finished product remains within the USP specified range (e.g., 3.5 to 7.0). The chemical name for methylprednisolone acetate is pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-11,17-dihydroxy-6-methyl-,(6α,11ß)- and the molecular weight is 416.51. The structural formula is represented below: Methylprednisolone acetate injectable suspension, USP contains methylprednisolone acetate, USP which is the 6-methyl derivative of prednisolone. Methylprednisolone acetate, USP is a white or practically white, crystalline powder which melts at about 213° with some decomposition. It is soluble in dioxane, sparingly soluble in acetone, alcohol, chloroform, and methanol, and slightly soluble in ether. It is practically insoluble in water. Methylprednisolone Acetate Chemical Srtucture