SPL Set ID: a07ed444-54e4-4d45-b6a1-6ea2f6dedc61
1 drug(s) with this SPL Set ID
Tramadol hydrochloride, USP is an opioid agonist in an extended-release tablet formulation for oral use. The chemical name is (±) cis-2-[(dimethylamino)methyl]-1-(3- methoxyphenyl) cyclohexanol hydrochloride. Its structural formula is: The molecular weight of tramadol HCl is 299.8. It is a white, bitter, crystalline and odorless powder that is readily soluble in water and ethanol and has a pKa of 9.41. The n-octanol/water log partition coefficient (logP) is 1.35 at pH 7. Tramadol hydrochloride extended-release tablets, USP contain 100, 200 or 300 mg of tramadol HCl in an extended-release formulation. The tablets are white to off-white in color and contain the inactive ingredients: microcrystalline cellulose, ethyl cellulose, hypromellose, magnesium stearate, polyethylene glycol. The imprinting ink opacode black contains shellac glaze, black iron oxide and ammonium hydroxide str