SPL Set ID: a02ca527-bd8f-49ef-89fa-91fac154bffe
1 drug(s) with this SPL Set ID
Rufinamide is a triazole derivative structurally unrelated to currently marketed antiepileptic drugs (AEDs). Rufinamide has the chemical name 1-[(2,6-difluorophenyl)methyl]-1H- 1,2,3-triazole-4 carboxamide. It has an empirical formula of C 10 H 8 F 2 N 4 O and a molecular weight of 238.2. The drug substance is a white to off white colour powder. Rufinamide is slightly soluble in tetrahydrofuran and in methanol; very slightly soluble in alcohol and in acetonitrile; practically insoluble in water. Rufinamide is available for oral administration as a liquid containing rufinamide at a concentration of 40 mg/mL. Inactive ingredients include citric acid anhydrous, colloidal silicon dioxide, hydroxyethylcellulose, hypromellose, lactose monohydrate, methylparaben, magnesium stearate, microcrystalline cellulose (GR101), microcrystalline cellulose and carboxymethylcellulose sodium, noncrystallizing sorbitol solution 70%, orange flavor, potassium sorbate, propylene glycol, propyl paraben, purified water and simethicone emulsion 30%. ruf-api