SPL Set ID: 9f00b2c9-e628-4265-8530-3258dd3cdcd5
1 drug(s) with this SPL Set ID
Doxycycline Hyclate Tablets, USP contain doxycycline hyclate, USP a tetracycline class drug synthetically derived from oxytetracycline, in an immediate release formulation for oral administration. The molecular formula of doxycycline hyclate is (C 22 H 24 N 2 O 8 · HCl) 2 · C 2 H 6 O · H 2 O and the molecular weight of doxycycline hyclate is 1025.87. The chemical name for doxycycline hyclate is: 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride, compound with ethyl alcohol (2:1), monohydrate. The structural formula for doxycycline hyclate is: Figure 1: Structure of Doxycycline Hyclate Doxycycline hyclate, USP is a yellow crystalline powder soluble in water and in solutions of alkali hydroxides and carbonates. Doxycycline Hyclate Tablets, USP: Doxycycline hyclate, USP is available as 75 mg and 150 mg tablets. Each 75 mg tablet contains 86.6 mg of doxycycline hyclate, USP equivalent to 75 mg of doxycycline, USP. Each 150 mg tablet contains 173.2 mg of doxycycline hyclate, USP equivalent to 150 mg of doxycycline, USP. Inactive ingredients in the tablet formulation are: silicified microcrystalline cellulose, sodium lauryl sulfate and magnesium stearate. Film-coating contains: hypromellose, titanium dioxide, polyethylene glycol, FD&C Blue #2 (75 mg Tablet), FD&C Yellow #6 (75 mg Tablet), FD&C Blue #2 (150 mg Tablet) and yellow iron oxide (150 mg Tablet). Doxycycline hyclate tablets, USP 75 mg contain 0.03 mg (0.0013 mEq) of sodium. Doxycycline hyclate tablets, USP 150 mg contain 0.06 mg (0.0026 mEq) of sodium. Doxycycline hyclate tablets meets USP Dissolution Test 3. structure