SPL Set ID: 9a3bfc59-0ca6-4433-abf5-41659bfe0a8f
1 drug(s) with this SPL Set ID
Montelukast sodium, the active ingredient in montelukast sodium oral granules USP, is a selective and orally active leukotriene receptor antagonist that inhibits the cysteinyl leukotriene CysLT 1 receptor. Montelukast sodium is described chemically as [ R -( E )]-1-[[[1-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl] cyclopropaneacetic acid, monosodium salt. The molecular formula is C 35 H 35 ClNNaO 3 S, and its molecular weight is 608.18. The structural formula is: Montelukast sodium is a hygroscopic, optically active, white or almost white powder. Montelukast sodium is soluble in water, methanol, ethanol and practically insoluble in acetonitrile. Each packet of montelukast sodium 4 mg oral granules USP contains 4.2 mg montelukast sodium USP, which is equivalent to 4 mg of montelukast. The oral granule formulation contains the following inactive ingredients: hydroxypropyl cellulose, magnesium stearate, and mannitol. Chemical Structure