SPL Set ID: 992e66b7-525a-4bf8-bce7-6b29cb120378
1 drug(s) with this SPL Set ID
TENORETIC ® (atenolol and chlorthalidone) is for the treatment of hypertension. It combines the antihypertensive activity of two agents: a beta 1 -selective (cardioselective) hydrophilic blocking agent (atenolol, TENORMIN ® ) and a monosulfonamyl diuretic (chlorthalidone). Atenolol is Benzeneacetamide, 4-[2'-hydroxy-3'-[(1-methylethyl) amino] propoxy]-. Atenolol (free base) is a relatively polar hydrophilic compound with a water solubility of 26.5 mg/mL at 37°C. It is freely soluble in 1N HCl (300 mg/mL at 25°C) and less soluble in chloroform (3 mg/mL at 25°C). Chlorthalidone is 2-Chloro-5-(1-hydroxy-3-oxo-1-isoindolinyl) benzene sulfonamide: Chlorthalidone has a water solubility of 12 mg/100 mL at 20°C. Each TENORETIC 100 Tablet contains: Atenolol (TENORMIN ® ).......................................100 mg Chlorthalidone........................................................ 25 mg Each TENORETIC 50 Tablet contains: Atenolol (TENORMIN ® ).........................................50 mg Chlorthalidone..........................................................25 mg Inactive ingredients: magnesium stearate, microcrystalline cellulose, povidone, sodium starch glycolate.