SPL Set ID: 977b2395-14ff-4c64-9a1e-77ef75805a83

Clindamycin Phosphate and Benzoyl Peroxide Gel, 1.2% / 2.5% is a combination product with two active ingredients in a white to off-white, opaque, smooth, aqueous gel formulation intended for topical use. Clindamycin phosphate is a water-soluble ester of the semi-synthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent antibiotic lincomycin. The chemical name for clindamycin phosphate is Methyl 7 chloro-6,7,8-trideoxy- 6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo a-D-galacto octopyranoside 2- (dihydrogen phosphate). The structural formula for clindamycin phosphate is represented below: Clindamycin phosphate: Molecular Formula: C 18 H 34 CIN 2 O 8 PS Molecular Weight: 504.97 Benzoyl peroxide is an antibacterial and keratolytic agent. The structural formula for benzoyl peroxide is represented below: Benzoyl peroxide: Molecular Formula: C 14 H 10 O 4 Molecular Weight: 242.23 Clindamycin Phosphate and Benzoyl Peroxide Gel, 1.2% / 2.5% contains the following inactive ingredients: carbopol 980, poloxamer 182, polysorbate 80, propylene glycol, purified water and sodium hydroxide. Each gram of Clindamycin Phosphate and Benzoyl Peroxide Gel, 1.2% / 2.5% contains 1.2% of clindamycin phosphate which is equivalent to 1% clindamycin. clinda-str benzoyl-str