SPL Set ID: 93dd604f-8f38-4600-afe8-0fcc92fd2497
1 drug(s) with this SPL Set ID
Tadalafil tablets USP, an oral treatment for pulmonary arterial hypertension, are a selective inhibitor of cyclic guanosine monophosphate (cGMP)–specific phosphodiesterase type 5 (PDE5). Tadalafil USP has the empirical formula C 22 H 19 N 3 O 4 representing a molecular weight of 389.41. The structural formula is: The chemical designation is pyrazino[1´,2´:1,6]pyrido[3,4–b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-, (6R,12aR)-. It is a crystalline solid that is practically insoluble in water and very slightly soluble in ethanol. Tadalafil tablets USP are available as yellow coloured, almond shaped, biconvex film coated tablets having ‘L64’ debossed on one side and plain on other side for oral administration. Each tablet contains 20 mg of tadalafil USP and the following inactive ingredients: colloidal silicon dioxide, croscarmellose sodium, hypromellose 6 cPs, iron oxide yellow, lactose monohydrate, microcrystalline cellulose, povidone, sodium citrate dihydrate, sodium lauryl sulphate, sodium stearyl fumarate, talc, titanium dioxide, and triacetin. str